Open Windows Explorer and copy and paste one of the following locations into the address bar:Ĭlearing Office Document Cache for Office 2016 %localappdata%\Microsoft\Office\16.0\OfficeFileCache Clearing Office Document Cache for Office 2013 %localappdata%\Microsoft\Office\15. It can often be resolved by clearing the Office Document Cache. This issue can be caused by problems with the Office Document Cache. The workbook you are trying to save has the same name as a currently open workbook. The file is being used by another program. Microsoft Excel cannot access the file ‘’. The error displays two messages, the first is: 
You may experience an issue that prevents you from opening Excel documents via SharePoint Online. Microsoft Excel cannot access the file on SharePoint 'Msosync.exe' is the Microsoft Office Document Cache (ODC) synchronizer and cache management program, introduced with Office 2010 to enhance interaction of Excel, Word, and PowerPoint with SharePoint Workspace (SPW), OneDrive for Business (ODFB), and other network and Web-based collaboration systems.
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